There are many factors that contribute to this, but I can strongly assure you that a diet including a moderate amount of healthy ripe fruits is not one of them. The fruits are actually part of the cure for cancer. There are four primary contributors to mitochondrial dysfunction:
Excess linoleic acid (LA).
Estrogen dominance.
EMFs.
Endotoxin.
These all play major roles, but excess LA and estrogen dominance are clearly the leading contributors resulting in the vast majority of cancers resulting from mitochondrial dysfunction. This is largely because LA and estrogen negatively impact your body in many similar ways. They both:.
Increase free radicals that cause oxidative stress and damage your mitochondria’s ability to produce energy.
Increase calcium intake inside the cell that causes an increase in nitric oxide and superoxide that increases peroxynitrite that also increases oxidative stress.
Cause an increase in intracellular water causing your body to retain water.
Slow down your metabolic rate and suppress your thyroid gland.
Nearly everyone in the developing world has 10 times the amount of LA in their tissues than their ancestors of 100 years ago had. This PUFA is very susceptible to oxidative damage and produces free radicals like reactive aldehydes in your body that destroy your mitochondria.
These toxic metabolites of LA create enormous amounts of reductive stress as a result of electrons building up in the ETC and blocking the forward movement of electrons to complex IV and V to create ATP.
And, because LA is embedded in the inner mitochondrial membrane, it gets damaged and leaks protons that normally build up in the inner mitochondrial space. This proton gradient is responsible for driving the nano motor in complex V to create ATP. Both processes combine to shut down and ultimately prematurely destroy the mitochondria.
Finally, when you eat carbs like starches, they can end up feeding bacteria in the intestine, which creates endotoxin that is a potent mitochondrial poison.
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